Bryan Armetta recommended betting Pirates minus 1.5 runs (+124) on Opening Day, highlighting Pittsburgh’s clear pitching and hitting advantages over Miami. The Pirates send reigning NL Rookie of the Year Paul Skenes to the mound, facing the Marlins' Sandy Alcantara, who makes his first start in over a year. Offensively, the Pirates bolstered their team by adding Spencer Horowitz and Tommy Pham, whereas Miami significantly weakened, trading away slugger Jake Burger and losing Connor Norby to an oblique injury. Armetta cited Pittsburgh’s total domination of the season series last year (7-0), concluding that this trend is likely to continue given the current matchup disparities.

Bryan Armetta is confident backing the Giants on the moneyline (-110) on Opening Day, emphasizing pitcher Logan Webb's consistent performance over his career. Webb owns impressive career stats, including a 3.18 ERA, 2.99 FIP and 1.14 WHIP. His dominance extends specifically to matchups against Cincinnati, with a stellar 1.64 ERA and 30 strikeouts over 6 starts. By contrast, the Reds' starter Hunter Greene, though talented, is erratic and struggles with control––an issue likely exacerbated by colder conditions. Additionally, the Giants upgraded their lineup by adding All-Star shortstop Willy Adames. Cincinnati's relatively quiet offseason further solidifies San Francisco as the safer wager.

Bryan Armetta advised backing the Twins at minus 1.5 runs (+145), citing Minnesota's substantial pitching edge and lineup strength against the Cardinals. Twins' starter Pablo Lopez brings reliability to the mound, while St. Louis' Sonny Gray had a rough spring training, struggling to a concerning 12.56 ERA over four appearances. Although spring stats can mislead, Gray's prolonged struggles remain alarming. The Twins will feature star hitters Byron Buxton and Carlos Correa, while the Cardinals enter the season with roster stagnation, failing to trade dissatisfied veteran Nolan Arenado. Given these pitching disparities and Minnesota's clear talent advantage, Armetta expects a comfortable Twins victory.