Eric Uribe advised bettors to back San Francisco −13.5 on Monday night. He argued the spread is warranted because Brock Purdy continues to pick apart defenses with a quick-strike passing attack while Christian McCaffrey punishes opponents on the ground and through the air. With Deebo Samuel and Brandon Aiyuk stretching the field horizontally and vertically, Uribe expects Kyle Shanahan to dictate tempo from the opening drive. On the other side, Carolina has struggled to protect Bryce Young all season and now faces one of the NFL’s deepest defensive lines. Uribe noted that the 49ers rank near the top of the league in pressure rate and routinely collapse pockets, a nightmare for a Panthers offense already short on explosive plays. Given the talent gap on both sides of the ball and San Francisco’s playoff urgency, Uribe sees a multi-score Niners win as the most likely script and is comfortable laying nearly two touchdowns.