Jason La Confora said he would not be surprised if Nick Emmanwori is the second defensive back selected and sneaks into the top‑10 picks. He named both the 49ers and Dolphins as realistic landing spots and stressed that front offices are much higher on Emmanwori than public mock drafts indicate. La Confora added that teams are looking for hybrid safeties who can handle slot duties and erase the motion‑heavy concepts dominating today’s NFL, so it does not have to be a pure cornerback who comes off the board first. Bettors playing first‑defensive‑back or top‑10 props should treat Emmanwori as a live option rather than a long‑shot.

Jason La Confora advocated taking the 8.5‑to‑1 odds on a defensive lineman being the Jets’ first pick, forecasting Michigan star Mason Graham as the target if he slips. La Confora noted Robert Saleh’s defense collapsed from 2nd to 18th in run‑stop DVOA and allowed 4.9 yards per carry over the final eight games. With Graham posting a 90.3 PFF run‑defense grade and a 14% pressure rate—elite numbers for a true sophomore—La Confora believes Saleh will push hard for an interior anchor. He emphasized that the 2025 class is considered generational on the defensive line, so grabbing the last blue‑chip tackle before a tier drop makes strategic sense. If two tackles, one running back, and at least one quarterback go ahead of pick 7, Laplacly expects Graham to be staring them in the face, making the long‑shot price a bargain.

Jason La Confora revealed he has already wagered on Tetairoa McMillan to go exactly sixth overall, calling the +750 to +900 prices still available “too good to pass.” He reasoned that minority owner Tom Brady spent two decades begging Bill Belichick for perimeter weapons and now sits in a draft room with the chance to grab the class’s cleanest outside separator. La Confora added that Pete Carroll joined the front office after watching DK Metcalf terrorize defenses and will advocate for a similar profile. With Brock Bowers already in house and the club holding extra Day‑2 picks, doubling up at tight end is unlikely. La Confora is unconcerned about mock‑draft pundits calling McMillan an overdraft; he emphasized the Raiders rank bottom‑three in EPA on throws beyond 15 yards and that McMillan’s 4.46 speed and 88th‑percentile wingspan directly solve that issue.

Jason La Confora urged listeners to leave a little draft‑position money on Ashton Jeanty going fifth overall to Jacksonville. He argued former All‑Pro tackle Tony Boselli now advises ownership and will pound the table for a run‑game tone‑setter after watching Travis Etienne finish 30th in explosive‑run rate. New play‑caller Dave Canales has publicly stressed balancing Trevor Lawrence with a downhill ground game—his Seattle offenses averaged 26 rushes a week with far less talent. La Confora ran the idea by long‑time Jaguars insider Pete Prisco, who confirmed the staff views Jeanty as a “difference maker.” Combining front‑office admiration with the scarcity of true three‑down backs, La Confora believes the +650 to +800 range on Jeanty’s draft slot is mispriced and worth a sprinkle.

Jason La Confora recommended betting wide receiver at +225 for the Cowboys’ first selection. He reminded listeners that Dak Prescott’s 2024 cap hit is north of $60 million and Dallas must maximize the passing game while they figure out an extension. Jerry Jones has a history of nailing first‑round WRs (CeeDee Lamb, Dez Bryant) and loves the publicity splash. La Confora argued adding an X like Texas’ Isaiah Bond or LSU’s Malik Nabers would force defenses to pick their poison against Lamb, creating a more efficient offense than simply replacing Zack Martin at guard. Given Jones’ autonomy, La Confora sees WR as the most likely and most profitable angle.

Jason La Confora pushed back on the D‑line consensus and suggested taking the +400 flier on the 49ers opening with a defensive back—either South Carolina’s Nick Emmanwori or the top corner on the board. La Confora cited league feedback that there are starter‑grade defensive tackles in every round, whereas position‑less DBs who can erase Kyle Shanahan’s scheme‑killers (think Kyle Hamilton vs. Brock Purdy) are rare. With Mike Macdonald now in the division, La Confora expects a chess‑match for hybrid safeties and thinks Lynch’s own background in the secondary nudges him toward an impact DB if the right one falls.

Jason La Confora urged listeners to ignore the recent drift to +110 and still back quarterback as the Saints’ first‑drafted position, because he is convinced New Orleans will take Shedeur Sanders ninth overall. La Confora argued Mickey Loomis cannot run a "faceless, boring" operation much longer— the franchise needs a marketable signal‑caller with Derek Carr both injured and expensive. He pointed to Denver’s success handing Sean Payton a maligned college QB (Bo Nix) as proof front offices will ignore Twitter scouting reports. La Confora played the prop at +1100 in March and still believes Sanders is the clear QB2 in this class, easily beating out Spencer Rattler. Even if Sanders red‑shirts behind Carr, the pick sells hope and resets the cap, making quarterback the highest‑EV wager on the Saints’ menu.