Lindquist targeted Anthony Santander’s home-run prop against Ryan Pepiot, arguing that Pepiot’s heavy four-seamer/changeup mix plays worse against left-side swings. Santander will bat from his stronger left side, and although his barrel rate has dipped to 4.6 % through only 108 batted balls, Lindquist expects that to normalize toward last year’s 11.7 % with more reps. Pepiot’s change has surrendered a .463 xSLG to lefties, and Tropicana Field’s controlled environment removes the weather variables that often cap power upside. With Santander likely hitting third and avoiding Rays platoon shenanigans, Lindquist prefers his HR market if books hang +475 or longer, viewing it as undervalued given the matchup and Santander’s historical power profile.

Donaldson wagered one unit on an Anthony Santander home run and three units on over 1.5 H+R+RBI. He called Santander’s recent slump misleading, highlighting several foul rockets and underlying metrics that point to an imminent power surge. Tuesday’s game featured multiple 100-mph fouls, convincing Rob that the timing is a fraction off and the breakout is coming—especially against Ryan Pepiot’s fastball-heavy arsenal, which lines up with Santander’s pull-side power.

Joe Pisapia backed Anthony Santander to go deep again Thursday, highlighting that the switch-hitter has homered in two of his last three games and is finally squaring balls up after pressing during his first month in Toronto. Pisapia said he watched every plate appearance last night and noted multiple 105-mph exit velocities, a sign Santander’s timing has clicked. With the swing path built for Rogers Centre’s right-field porch and a middling opposing lefty on the mound, Pisapia likes Santander’s HR prop at anything north of +400 and would consider him a low-owned DFS one-off for those chasing power.

Pisapia told the chat he is "buying Anthony Santander everywhere." While many managers are frustrated after Santander’s slow April, Pisapia pointed out that the outfielder has now homered on back-to-back days and historically heats up once the calendar flips to May. Given the underlying power track record (30-plus homers in two of the last three seasons) and the fact that his barrel rate is already climbing, Pisapia believes this is the last chance to acquire a middle-of-the-order bat at a discount before the hot streak fully arrives.

Joe Pisapia tagged Anthony Santander for another home-run call, saying the veteran finally looks locked in after adjusting to a new city and fresh contract. Pisapia watched every plate appearance Tuesday and said Santander "hit that ball country-mile hard," citing back-to-back barrels at 104 mph and 107 mph. Now that his launch angle has crept back to the 13-degree range that fueled 95 RBI last season, Pisapia is confident the slugger’s May OPS spike (up 140 points over April) is real. He advised bettors to ride Santander HR props and DFS managers to squeeze him into lineups before his salary climbs.

Guy Boston sees strong betting value in Anthony Santander under 1.5 total bases today. Santander has only exceeded 1.5 total bases once or twice all season so far, including just a single hit in Game 1 against the Red Sox. Historically against Walker Buehler, Santander carries a .200 batting average in six plate appearances but just one total base amassed. Boston emphasized swing-and-miss potential as a necessity for Buehler in this matchup, highlighting Santander's struggles versus right-handed pitching. Given Santander's poor overall production to start the season combined with Buehler's potential to limit him effectively, Boston expects the under to cover comfortably.

Guy Boston is cautious but leaning toward Anthony Santander's under 1.5 bases today against Boston pitcher Richard Fitz. Fitz relies heavily on fastballs and sliders—two offerings Santander notably struggles to consistently hit. However, Guy Boston highlighted the significant concern of a potential mismatch because Fitz's preferred fastball location (high and outside) matches up perfectly with Santander's batting hot spot from last year's data. Thus, while the pitch-type matchup favors the under, the location potential poses substantial risk, making this fade a bit dicey.

Eric Lindquist expects Anthony Santander to bounce back offensively despite a rocky start. Lindquist highlighted Santander's concerning early-season barrel rate of just 5%, significantly below last year's 11.7%, and his hard-hit rate dipping from 41.6% down to 30%. Despite these early quality contact issues, Lindquist predicts positive regression, underscoring Santander's favorable historical performance from the left side of the plate, combined with today's favorable wind conditions blowing out to right field. He strongly recommends betting Santander to record at least one hit as a high-confidence parlay piece at -146 odds, advising not going beyond -160.

Matt Perrault sees Anthony Santander as a strong value play to exceed 1.5 total bases against Washington Nationals pitching. Despite Santander only clearing this total once in four games this season, Perrault pointed out that the Nationals pitching staff, specifically Michael Soroka, represents a favorable matchup and an opportunity for success. Additionally, the prop bet cheat sheet from BettingPros Premium supports this play, giving added confidence to the bet at plus-money odds (+105).

B Wade recommends fading Anthony Santander's run-scoring potential (under 0.5 runs) against Baltimore starter Charlie Morton. Santander is historically 0-for-6 with a 50% strikeout rate against Morton, demonstrating previous difficulties facing this pitcher. Additionally, despite Santander scoring runs in about 46% of his games last season, B Wade emphasized Toronto's weak lineup behind Vladimir Guerrero, highlighting that last season only one Blue Jay batter had RBI totals comparable to the Orioles, making it difficult for Santander to reliably score runs even if he reaches base. Santander also went 0-for-4 without getting on base in the season opener, further supporting this under bet.