Matt LaMarca highlighted Tony Pollard as the second-best FanDuel Plus/Minus among RBs at just $5,900. With Tyjae Spears on IR, Pollard played 89% of snaps and handled 86% of designed rushes in Week 1. Although Tennessee failed to score a TD versus Denver, LaMarca expects efficiency to rebound against a Rams defense that finished 20th in rush-defense EPA last season. Massive share of touches plus discounted salary equals slate-breaking ceiling if the Titans offense merely shows up.

Matt LaMarca labeled Kyren Williams a priority tournament play at $6,300 after he logged 81% of snaps and 18 of 19 backfield carries in Week 1 while running a route on 53% of dropbacks. With the Rams installed as 5.5-point favorites in Tennessee, Williams draws the game-script LaMarca says has driven his production: 19.74 DK points and a +4.93 Plus/Minus when favored. The Titans allowed the 20th-worst rush-defense EPA in 2024, giving Williams both secure volume and multi-TD upside at modest ownership.

Max Chadwick targeted under 18.5 rushing attempts for Tony Pollard at -120 on Fanatics, citing a PFF projection of just 13.6 carries. Pollard hit 18 attempts in Week 1, but that came while rookie quarterback Cam Ward faced Denver’s elite secondary, forcing a conservative plan. Against the Rams, Chadwick expects Tennessee to lean on Ward’s arm because Los Angeles is tougher against the run than the pass. The anticipated shift in offensive balance plus the sizeable projection gap makes the under his preferred side.

Dabbundo took Titans +5.5, stressing how both Rams starting guards—Steve Avila and Kevin Dotson—are week-to-week with sprained ankles. That leaves Matthew Stafford facing Jeffrey Simmons and an elite Tennessee interior that just limited Denver to 4.0 YPA and a 6-for-17 mark on third/fourth down. Los Angeles managed only 14 points at home last Sunday even with a healthy line; last year they opened 1-4 when multiple OL starters were sidelined. Tennessee’s own offense looked ugly on the stat sheet, but Dabbundo thought Cam Ward handled a brutal road spot reasonably well and expects improvement if tackle JC Latham (ankle) suits up. Given the trench mismatch and historically low-scoring profile, he labeled the Titans a 'live dog' catching more than a field goal.

James Boutros recommended Tony Pollard over 67.5 rushing yards (-113), noting that the Titans’ opener was a worst-case matchup against Denver’s elite run defense that still produced 18 carries, a 60-yard day, and an 89% snap share for Pollard. Boutros argued the Rams do not pose the same resistance, setting up a bounce-back spot where Tennessee’s run-first identity can actually pay dividends. With volume locked in and a friendlier defensive front in front of him, Boutros projects Pollard well into the 70- to 80-yard range.

Taking +6 (–105, BetMGM), MacMillan is buying low on Tennessee after Cam Ward’s rough road debut versus an elite defense. He noted the Rams ranked just 24th in offensive EPA despite winning, while Tennessee’s defense sat 5th in opponent EPA and 6th in success rate. With that pass rush keyed on an "underperforming" Matthew Stafford, MacMillan expects the Titans to stay inside the number.

Dave Loughran leaned toward Titans +5.5 (grab +6 if it pops). He expects Tennessee’s defensive front—fresh off rattling Bo Nix—to limit Kyron’s rushing lanes and force Matthew Stafford to lean on a one-dimensional passing attack that funneled 66 percent of targets to just Puka Nacua and Davante Adams in Week 1. With top pick Cam Ward predictably struggling in Denver’s altitude last week, Loughran still trusts a Titans defense that can shrink possessions and keep things tight while Ward acclimates.

John Middlekauff advised grabbing Tennessee +5.5 against the visiting Rams. He insisted the Titans "aren’t bad" and said the number is inflated because L.A. looked good in Week 1. Middlekauff’s core angle is the classic West-Coast-team-flying-east fade: the Rams must cross four time zones for a 10 a.m. body-clock kickoff after an emotional win, a spot he claims consistently produces flat starts. With Tennessee at home and catching more than a field goal, he expects a slugfest that could be tied entering the fourth quarter. While he would sprinkle the moneyline, Middlekauff called the points the smarter investment.