Wes Reynolds advised grabbing Jacksonville +3.5 at San Francisco. Although Brock Purdy has been cleared to start, Reynolds stressed that the 49ers are dangerously thin: Brandon Aiyuk is still on IR, George Kittle is out, Jauan Jennings and rookie Ricky Pearsall have yet to practice, and star edge rusher Nick Bosa tore his ACL last week. The market bumped the spread only half a point on Purdy news, signaling limited confidence. San Francisco’s 3-0 record has come by margins of 4, 5 and 1 points, a profile Reynolds says is ripe for close-game regression. On the other side, Jacksonville’s issues are correctable—Trevor Lawrence’s four interceptions (second-most in the league) and the Jags’ league-leading 13 drops—yet the roster is largely healthy. With the 49ers offense missing key weapons and the defense minus its best pass-rusher, Reynolds expects Jacksonville to stay within a field goal, making the hook at +3.5 valuable.