Andy Lang recommended betting the 49ers over 10.5 wins, calling their 2025 slate “one of the craziest schedules I’ve seen.” He rattled off a run of opponents—Seahawks, Saints, Cardinals, Jaguars, Rams, Buccaneers, Falcons, Texans, Giants, Panthers, Browns, Titans, Colts and Bears—and argued the only matchup that looks remotely scary on paper is at Tampa Bay. Lang backed up the bullish view with Pro Football Focus grades that had last year’s six-win 49ers fourth in offensive efficiency, 15th on defense, 10th on special teams, 12th on the offensive line and 21st on the defensive line. He noted Kyle Shanahan–coached teams routinely rip off post-bye winning streaks, so even a slow start could flip fast. If Brock Purdy and Christian McCaffrey stay healthy, Lang expects a double-digit win total to come easily and is willing to accept injury risk for the payout on the over.